By Dr. Ch. Chouchkov (auth.)
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Extra info for Cutaneous Receptors
Nervenregeneration und verwandte Innervationsprobleme. Ergebn. d. Physio!. : Nerve endings, motor and sensory. In: Cytology and Cellular Pathology of the Nervous System. Penfield, W. ), New York: Hoerber, 1932, pp. : Die Apparate des Gefiihlsinnes der nackten und behaarten Siiugetierhaut, mit Beriicksichtigung des Menschen. Anat. Anz. 42, 193-205 (1912) Breathnach, A. : Ultrastructural observations on Merkel cells in human fetal skin. 1. Anat. , Horch, K. : Specific regeneration of cutaneous fibres in the cat.
Phosphatases Most of the encapsulated receptors show a generalized reaction to alkaline phosphatase when tissue slices are treated with either the cobalt sulphide or the azo-dye technique. The reaction is localized in the capillary wall and on the Schwann receptor cells around the nerve fibres, which themselves are unreactive (Giacometti and Machida, 1965; Chouchkov, 1968b; Ulumbekov, 1974). After the experimental denervation of the pacini an corpuscles (Chouchkov and Davidoff, 1970b) the enzyme activity changes parallel with the onset of degeneration amongst the Schwann receptor cells.
1973; Ulumbekov, 1974). The strongest activity of the receptor nerve fibres correlates with the abundance of tightly packed mitochondria in these areas. The functional activity of mitochondria has been considered important in the supply of energy required for the transduction of physical stimuli into sensory nerve impulses (Bleichmar and De Robertis, 1962). On the other hand, recent studies (Weiss and Mayr, 1972) have suggested that mitochondria at neuronal terminations, such as the presynaptic endings of motor end-plates, lose their viability by undergoing a massive and rapid degeneration.