Design, Modeling and Characterization of Bio-Nanorobotic by Mustapha Hamdi

By Mustapha Hamdi

Nanorobots characterize a nanoscale gadget the place proteins resembling DNA, carbon nanotubes may well act as vehicles, mechanical joints, transmission components, or sensors. while those assorted elements have been assembled jointly they could shape nanorobots with multi-degree-of-freedom, capable of observe forces and control gadgets within the nanoscale global. Design, Modeling and Characterization of Bio-Nanorobotic structures investigates the layout, meeting, simulation, and prototyping of organic and synthetic molecular buildings with the aim of enforcing their inner nanoscale events inside of nanorobotic structures in an optimized manner.

Design, Modeling and Characterization of Bio-Nanorobotic Systems focuses, usually on techniques. the 1st one contains multiscale modeling instruments (quantum mechanics, molecular dynamics, continuum mechanics) coupled to digital fact complicated strategies. so as to layout and assessment the features of molecular robots, we proposed interactive nanophysics-based simulation which allows manipulation of molecules, proteins and engineered fabrics in molecular dynamics simulations with real-time strength suggestions and graphical exhibit. the second one method makes use of a unique co-prototyping method, the place the nanorobotic’s multiscale version is coupled to experimental measurements.

Design, Modeling and Characterization of Bio-Nanorobotic Systems provides a unique proposal of nanorobots, bio-nanoactuators dependent DNA and rotating nanodevices dependent carbon nanotubes. furthermore the offered platform helped to signify the interplay among novel drug supply platforms and mobile membrane.

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It is a doublehelical biopolymer, Fig. 15, in which two chains of complementary nucleotides (the subunits whose sequence constitutes the genetic message) wind (usually righthandedly) around a common axis to form a double-helical structure [68]. Because of this unique structure, the elastic property of DNA molecule influences its biological functions greatly. There are mainly three kinds of deformations in DNA double-helix: stretching and bending of the molecule, twisting of one nucleotide chain relative to its counterpart.

This device is essentially a mouse mounted on a mechanical arm. It can be pushed around in three dimensions and, by way of a clever arrangement of small motors, it can push back. 32 1 Current State-of-the-Art on Nanorobotic Components and Design Fig. 30 (a) Molecules can be grasped with a cyberglove and moved to a desired position. (b) 3-D menu can be activated and selected by a gesture of the cyberglove (reprinted from: Z. Ai, T. Frohlich) Once users “attach” to an atom using the haptic interface, they can feel the attractive and repulsive forces as this atom pushes and pulls on its neighbors.

Although kinesin is also a two-headed linear motor, its modus operandi is different from myosin in the sense that both of its heads work together in a coordinated manner in contrast to one being left out in the case of myosin. 19(b) shows the kinesin walk. Each of the motor heads is near the microtubule in the initial state, with each motor head carrying an ADP molecule. When one of the heads loosely binds to the microtubule, it loses its ADP molecule to facilitate a stronger binding. Another ATP molecule replaces the ADP, which facilitates a conformational change such that the neck region of the bound head snaps forward and zips on to the head, (courtesy C.

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